Nikolas Dovrolis

Assistant Professor of Medical Biology

Biomedical scientist and computational biologist with long-standing experience in translational omics, systems biology and precision medicine. Research activity focuses on mechanisms of human disease, with emphasis on inflammatory bowel disease, tissue remodeling and fibrosis, microbiome-host interactions, molecular oncology, viral genomics, cardiovascular molecular phenotyping, drug repositioning and biomarker discovery.

Email ORCID Google Scholar Scopus
61total publications
26first or shared-first author publications
10corresponding-author publications
18Google Scholar h-index
15Scopus h-index

Profile

Translational computational biology for human disease

Nikolas Dovrolis combines computational biology, statistical modelling, machine learning and experimental awareness to connect molecular signatures with clinical phenotypes, diagnostic and prognostic applications, and therapeutic hypotheses. His work spans gene expression, 16S rRNA and shotgun metagenomics, metatranscriptomics, metametabolomics, epigenetics, proteomics, multi-omics integration, survival analysis, network biology, graph-based methods, ligand-receptor inference, GWAS, polygenic risk modelling, WGS, WES, SNP-array analysis, variant interpretation, phylogenetics, meta-analysis and study design.

Core expertise

Research and methodological areas

Translational omics

Transcriptomics, single-cell analysis, metagenomics, proteomics, multi-omics integration and biological interpretation of high-dimensional biomedical datasets.

Microbiome and mucosal disease

Host-microbiome interactions in inflammatory bowel disease, microbial metabolites, tissue remodeling, fibrosis and stromal-myeloid cellular communication.

Precision medicine and biomarkers

Machine learning, survival modelling, biomarker discovery, patient stratification, response prediction and computational drug repositioning.

Genomics and virology

Viral genome analysis, virome characterization, virus-host interactions, SARS-CoV-2, hepatitis C, West Nile virus and arthropod vector viromes.

Molecular oncology

miRNA, gene expression and computational repositioning analyses in colorectal, renal, breast, pancreatic and endometrial cancer.

Experimental interface

qRT-PCR, microarray analysis, immunohistochemistry, immunofluorescence, nucleic-acid QC, NGS library preparation, flow cytometry, cell culture concepts, organoids, ELISA and pharmacological response assays.

Research and professional appointments

Appointments

  1. 2026-presentAssistant Professor of Medical Biology, Department of Medicine, Democritus University of Thrace

    Medical Biology.

  2. 2019-2026Postdoctoral Researcher, Department of Medicine, Democritus University of Thrace

    Computational Biology, microbiome and viral infection research.

  3. 2024-2026Associate Researcher, Bioinformatics Expert, Unified Diagnostics, MIT Sloan School of Management

    Diagnostic biomarker discovery, PI Dimitris Bertsimas.

  4. 2024-presentChief Bioinformatics Officer, Black Arrow Biotech

    AI and machine-learning approaches for peptide drug discovery and microbiome-based diagnostic and therapeutic biotechnology activities.

  5. 2023-2024Associate Researcher, H2020 KATY, National and Kapodistrian University of Athens

    Bioinformatics expert in the project Knowledge At the Tip of Your fingers: Clinical Knowledge for Humanity.

  6. 2021-2023Associate Researcher and Head of Bioinformatics Unit, Center of Excellence for Pharmacological Studies and Precision Medicine, DUTH

    Multi-omics, pharmacogenomics, precision medicine and systems bioinformatics.

  7. 2019-2021Associate Researcher, INSEQT, DUTH

    NGS-based genomic and transcriptomic screening of blood-feeding insects and associated pathogens.

  8. 2008-2013Associate Researcher, Department of Medicine, DUTH

    Semantic web, medical education technologies, comorbidity modelling, patient empowerment services and research proposal development.

Education

Degrees

2016, MSc, Translational Research in Molecular Biology and Genetics

Democritus University of Thrace. Thesis: Drug repositioning for neurodegenerative diseases.

2007, BSc, Computer Science

University of Ioannina.

1997, Cambridge Proficiency in English

Teaching, supervision and academic service

Teaching and mentorship

Postgraduate teaching

Invited lecturer since 2019 in postgraduate programmes at DUTH and NKUA, covering systemic bioinformatics, NGS and bioinformatics, microbiome analysis, medical statistics in infectious diseases, computational microbiome analysis and human microbiome genomics.

Undergraduate teaching

Independent undergraduate teaching in Biology, Genetics and Pharmacology I during 2024-2026, including lectures and laboratory or practical groups in medicine curricula.

MSc supervision

Supervisor of MSc theses in microbiome, clinical pharmacology, pharmacogenomics, metagenomics and transcriptome-guided drug repositioning during 2025-2026.

Funded research

Competitive projects

Senior researcher, statistics and bioinformatics expert in 8 funded or co-funded projects, including H2020 KATY, the Center of Excellence for Pharmacological Studies and Precision Medicine, INSEQT, HELCOHOP clinical protocols, the mEducator medical-education linked-data network, WideMEDnet and PERKA home-care telematics.

Roles covered bioinformatics unit leadership, multi-omics analysis, clinical and statistical analysis, NGS pipelines, RDF/schema development, technical deployment, training, deliverables, dissemination and evaluation.

Scientific publications

Selected peer-reviewed publications

  1. Lazaridis A*, Dovrolis N*, Katifelis H, Myoteri D, Vlahos I, Vlahos NF, Gazouli M. miRNA Signatures in Endometrial Cancer: Implications for Oncogenesis and Polymerase Epsilon (POLE) Mutation Status. International Journal of Molecular Sciences. 2025;26(21):10438. Shared first author.
  2. Dovrolis N, Spathakis M, Collins AR, Pandey VK, Uddin MI, Anderson DD, et al. Pan-Cancer Insights: A Study of Microbial Metabolite Receptors in Malignancy Dynamics. Cancers. 2024;16(24):4178. Corresponding author.
  3. Kokkotis G, Filidou E, Tarapatzi G, Spathakis M, Kandilogiannakis L, Dovrolis N, et al. Oncostatin M induces a pro-inflammatory phenotype in intestinal subepithelial myofibroblasts. Inflammatory Bowel Diseases. 2024;30(11):2162-2173.
  4. Dovrolis N, Valatas V, Drygiannakis I, Filidou E, Spathakis M, Kandilogiannakis L, et al. Landscape of Interactions between Stromal and Myeloid Cells in Ileal Crohn's Disease; Indications of an Important Role for Fibroblast-derived CCL-2. Biomedicines. 2024;12(8):1674. Corresponding author.
  5. Dovrolis N, Gazouli M, Rigal F, Whittaker RJ, Matthews TJ, Georgiou K, et al. Power-law scaling in intratumoral microbiota of colorectal cancer. Gut Pathogens. 2024;16. Corresponding author.
  6. Koustenis K*, Dovrolis N*, Viazis N, Ioannou A, Bamias G, Karamanolis G, Gazouli M. Insights into Therapeutic Response Prediction for Ustekinumab in Ulcerative Colitis Using an Ensemble Bioinformatics Approach. International Journal of Molecular Sciences. 2024;25(10):5532. Shared first author.
  7. Dovrolis N, Filidou E, Tarapatzi G, Kokkotis G, Spathakis M, Kandilogiannakis L, et al. Co-expression of fibrotic genes in inflammatory bowel disease; A localized event? Frontiers in Immunology. 2022;13:7810. Corresponding author.
  8. Dovrolis N, Kassela K, Konstantinidis K, Kouvela A, Veletza S, Karakasiliotis I. ZWA: Viral genome assembly and characterization hindrances from virus-host chimeric reads; a refining approach. PLoS Computational Biology. 2021;17(8):e1009304. Corresponding author.
  9. Dovrolis N, Michalopoulos G, Theodoropoulos GE, Arvanitidis K, Kolios G, Sechi LA, Eliopoulos AG, Gazouli M. The Interplay between Mucosal Microbiota Composition and Host Gene-Expression is Linked with Infliximab Response in Inflammatory Bowel Diseases. Microorganisms. 2020;8(3):438.
  10. Dovrolis N, Kolios G, Spyrou GM, Maroulakou I. Computational profiling of the gut-brain axis: microflora dysbiosis insights to neurological disorders. Briefings in Bioinformatics. 2017.
  11. Dovrolis N, Kolios G, Spyrou G, Maroulakou I. Laying in silico pipelines for drug repositioning: a paradigm in ensemble analysis for neurodegenerative diseases. Drug Discovery Today. 2017.
Full peer-reviewed journal article list from the updated CV
  1. Lazaridis, Alexandros*, Nikolas Dovrolis*, Hector Katifelis, Despoina Myoteri, Iakovos Vlahos, Nikos F. Vlahos, and Maria Gazouli. "miRNA Signatures in Endometrial Cancer: Implications for Oncogenesis and Polymerase Epsilon (POLE) Mutation Status." International Journal of Molecular Sciences 26, no. 21 (2025): 10438. (Equal contribution).
  2. Daghir-Wojtkowiak, Emilia, Javier Alfaro, and Fabio Massimo Zanzotto. "Leveraging knowledge for explainable AI in personalized cancer treatment: challenges and future directions." Frontiers in digital health 7 (2025): 1637195.
  3. Skouradaki, Evagelia, Giasemi Eptaminitaki, Evagelia Kirio, Apostolos Zaravinos, Nikolaos Dovrolis, and Stavroula Baritaki. "RKIP and tumor immune evasion: Remodeling the immunosuppressive tumor microenvironment." Biochimica et Biophysica Acta (BBA)-Reviews on Cancer (2025): 189481.
  4. Skouradaki, Evangelia, Apostolos Zaravinos, Maria Panagopoulou, Ekaterini Chatzaki, Nikolas Dovrolis&, and Stavroula Baritaki&. "Pan-cancer computational analysis of RKIP (PEBP1) and LKB1 (STK11) co-expression highlights distinct immunometabolic dynamics and therapeutic responses within the tumor microenvironment." International Journal of Molecular Sciences 26, no. 15 (2025): 7145. (Corresponding author).
  5. Koutromanos, Ilias, Evangelia Legaki, Nikolas Dovrolis, Efthimios Vassilopoulos, Arthur Stem, Vasilis Vasiliou, Elias Tzavellas, and Maria Gazouli. "Integrating gut microbiome and neuroplasticity genomics in alcohol use disorder therapy." Human Genomics 19, no. 1 (2025): 78.
  6. Dovrolis, N. &, Spathakis, M., Collins, A. R., Pandey, V. K., Uddin, M. I., Anderson, D. D., ... & Kolios, G. (2024). Pan-Cancer Insights: A Study of Microbial Metabolite Receptors in Malignancy Dynamics. Cancers, 16(24), 4178. (Corresponding author).
  7. Kokkotis, G., Filidou, E., Tarapatzi, G., Spathakis, M., Kandilogiannakis, L., Dovrolis, N., ... & Bamias, G. (2024). Oncostatin M induces a pro-inflammatory phenotype in intestinal subepithelial myofibroblasts. Inflammatory bowel diseases, 30(11), 2162-2173.
  8. Legaki, E.*, Dovrolis, N.*, Moscholiou, N., Koutromanos, I., Vassilopoulos, E., Dakanalis, A., ... & Tzavellas, E. (2024). Altered Expression of Neuroplasticity-Related Genes in Alcohol Addiction and Treatment. International Journal of Molecular Sciences, 25(21), 11349. (Equal contribution).
  9. Drygiannakis, I., Valatas, V., Filidou, E., Tzenaki, N., Archontoulaki, E., Dovrolis, N., ... & Koutroubakis, I. E. (2024). Low-Grade Activation of the Extrinsic Coagulation Pathway in Patients with Ulcerative Colitis. Digestive Diseases and Sciences, 69(10), 3773-3785.
  10. Dovrolis, N.&, Valatas V.&, Drygiannakis I., Filidou, E., Spathakis M., Kandilogiannakis, L., Tarapatzi, G., Arvanitidis, K., Bamias, G., ... & Kolios, G. (2024) Landscape of Interactions between Stromal and Myeloid Cells in Ileal Crohn's Disease; Indications of an Important Role for Fibroblast-derived CCL-2. Biomedicines. 12(8):1674. (Corresponding author).
  11. Dovrolis, N.&, Gazouli, M.&, Rigal, F., Whittaker, R. J., Matthews, T. J., Georgiou, K., ... & Triantis, K. A.& (2024). Power-law scaling in intratumoral microbiota of colorectal cancer. Gut Pathogens, 16. (Corresponding author).
  12. Bampali, M., Kouvela, A., Kesesidis, N., Kassela, K., Dovrolis, N., & Karakasiliotis, I. (2024). West Nile Virus Subgenomic RNAs Modulate Gene Expression in a Neuronal Cell Line. Viruses, 16(5), 812.
  13. Koustenis, K.*, Dovrolis, N.*, Viazis, N., Ioannou, A., Bamias, G., Karamanolis, G., & Gazouli, M. (2024). Insights into Therapeutic Response Prediction for Ustekinumab in Ulcerative Colitis Using an Ensemble Bioinformatics Approach. International Journal of Molecular Sciences, 25(10), 5532. (Equal contribution).
  14. Sidiropoulos, T.*, Dovrolis, N.*, Katifelis, H., Michalopoulos, N. V., Kokoropoulos, P., Arkadopoulos, N., & Gazouli, M. (2024). Dysbiosis Signature of Fecal Microbiota in Patients with Pancreatic Adenocarcinoma and Pancreatic Intraductal Papillary Mucinous Neoplasms. Biomedicines, 12(5), 1040. (Equal contribution).
  15. Spathakis, M., Dovrolis, N.&, Filidou, E., Kandilogiannakis, L., Tarapatzi, G., Valatas, V., ... & Vradelis, S. (2024). Exploring Microbial Metabolite Receptors in Inflammatory Bowel Disease: An In Silico Analysis of Their Potential Role in Inflammation and Fibrosis. Pharmaceuticals, 17(4), 492. (Corresponding author).
  16. Tasopoulou, K. M., Karakasiliotis, I., Argyriou, C., Bampali, M., Tsaroucha, A. K., Dovrolis, N., ... & Georgiadis, G. S. (2024). Next-generation sequencing of micrornas in small abdominal aortic aneurysms: miR-24 as a biomarker. Annals of Vascular Surgery, 99, 366-379.
  17. Dovrolis, N., Katifelis, H., Grammatikaki, S., Zakopoulou, R., Bamias, A., Karamouzis, M. V., ... & Gazouli, M. (2023). Inflammation and Immunity Gene Expression Patterns and Machine Learning Approaches in Association with Response to Immune-Checkpoint Inhibitors-Based Treatments in Clear-Cell Renal Carcinoma. Cancers, 15(23), 5637.
  18. Zikou, E.*, Dovrolis, N.*, Dimosthenopoulos, C., Gazouli, M., & Makrilakis, K. (2023). The Effect of Probiotic Supplements on Metabolic Parameters of People with Type 2 Diabetes in Greece, A Randomized, Double-Blind, Placebo-Controlled Study. Nutrients, 15(21), 4663. (Equal contribution).
  19. Atzemian, N., Dovrolis, N.&, Ragia, G., Portokallidou, K., Kolios, G., & Manolopoulos, V. G.& (2023). Beyond the Rhythm: In Silico Identification of Key Genes and Therapeutic Targets in Atrial Fibrillation. Biomedicines, 11(10), 2632. (Corresponding author).
  20. Dovrolis, N., Moschoviti, A., Fessatou, S., Karamanolis, G., Kolios, G., & Gazouli, M. (2023). Identifying Microbiome Dynamics in Pediatric IBD: More than a Family Matter. Biomedicines, 11(7), 1979.
  21. Portokallidou, K., Dovrolis, N.&, Ragia, G., Atzemian, N., Kolios, G., & Manolopoulos, V. G. (2023). Multi-omics integration to identify the genetic expression and protein signature of dilated and ischemic cardiomyopathy. Frontiers in Cardiovascular Medicine, 10. &Corresponding Author
  22. Dovrolis, N.&, Filidou, E., Tarapatzi, G., Kokkotis, G., Spathakis, M., Kandilogiannakis, L., ... & Kolios, G. (2022). Co-expression of fibrotic genes in inflammatory bowel disease; A localized event?. Frontiers in Immunology, 13, 7810. (Corresponding author).
  23. Rezasoltani, S., Aghdaei, H. A., Jasemi, S., Gazouli, M., Dovrolis, N., Sadeghi, A., ... & Feizabadi, M. M. (2022). Oral Microbiota as Novel Biomarkers for Colorectal Cancer Screening. Cancers, 15(1), 192.
  24. Pliakou, E., Lampropoulou, D. I., Dovrolis, N., Chrysikos, D., Filippou, D., Papadimitriou, C., ... & Gazouli, M. (2023). Circulating miRNA Expression Profiles and Machine Learning Models in Association with Response to Irinotecan-Based Treatment in Metastatic Colorectal Cancer. International Journal of Molecular Sciences, 24(1), 46.
  25. Moustafa, S., Kassela, K., Bampali, M., Dovrolis, N., Kakkanas, A., Beloukas, A., ... & Karakasiliotis, I. (2022). Hepatitis C Core Protein Induces a Genotype-specific Susceptibility of Hepatocytes to TNF-induced Death in vitro and in vivo. Viruses, 14(11), 2521.
  26. Triantafyllou, A., Dovrolis, N., Zografos, E., Theodoropoulos, C., Zografos, G. C., Michalopoulos, N. V., & Gazouli, M. (2022). Circulating miRNA expression profiling in breast cancer molecular subtypes: Applying machine learning analysis in bioinformatics. Cancer Diagnosis & Prognosis, 2(6), 739.
  27. Anatolou, D., Dovrolis, N.&, Ragia, G., Kolios, G., & Manolopoulos, V. G.& (2022). Unpacking COVID-19 Systems Biology in Lung and Whole Blood with Transcriptomics and miRNA Regulators. OMICS: A Journal of Integrative Biology, 26(11), 608-621. (Corresponding author).
  28. Talli, I*., Dovrolis, N.*, Oulas, A.*, Stavrakaki, S., Makedou, K., Spyrou, G. M., & Maroulakou, I. (2022). Novel clinical, molecular and bioinformatics insights into the genetic background of autism. Human Genomics, 16(1), 39. (Equal contribution).
  29. Stefanou, I. K.*, Dovrolis, N.*, Gazouli, M., Theodorou, D., Zografos, G. K., & Toutouzas, K. G. (2022). miRNAs expression pattern and machine learning models elucidate risk for gastric GIST. Cancer Biomarkers, 33(2), 237-247. (Equal contribution).
  30. Chaintoutis, S.C., Siarkou, V.I., Mylonakis, M.E., Kazakos, G.M., Skeva, P.N., Bampali, M., Dimitriou, M., Dovrolis, N., Polizopoulou, Z.S., Karakasiliotis, I. and Dovas, C.I., 2022. Limited cross‐species transmission and absence of mutations associated with SARS‐CoV‐2 adaptation in cats: A case study of infection in a small household setting. Transboundary and Emerging Diseases, 69(3), pp.1606-1616.
  31. Konstantinidis, K., Bampali, M., de Courcy Williams, M., Dovrolis, N., Gatzidou, E., Papazilakis, P., ... & Karakasiliotis, I. (2022). Dissecting the species-specific virome in Culicoides of Thrace. Frontiers in Microbiology, 13, 802577.
  32. Dovrolis, N., Nikou, M., Gkrouzoudi, A., Dimitriadis, N., & Maroulakou, I. (2022). Unlocking the Memory Component of Alzheimer’s Disease: Biological Processes and Pathways across Brain Regions. Biomolecules, 12(2), 263.
  33. Konstantinidis, K.*, Dovrolis, N.*, Kouvela, A., Kassela, K., Rosa Freitas, M. G., Nearchou, A., ... & Karakasiliotis, I. (2022). Defining virus-carrier networks that shape the composition of the mosquito core virome of a local ecosystem. Virus Evolution, 8(1), veac036. (Equal contribution).
  34. Gazouli, M.*, Dovrolis, N.*, Bourdakou, M. M., Gizis, M., Kokkotis, G., Kolios, G., ... & Bamias, G. (2021). Response to Anti-α4β7 Blockade in Patients With Ulcerative Colitis Is Associated With Distinct Mucosal Gene Expression Profiles at Baseline. Inflammatory Bowel Diseases. (Equal contribution).
  35. Dovrolis, N.&, Kassela, K., Konstantinidis, K., Kouvela, A., Veletza, S., & Karakasiliotis, I. (2021). ZWA: Viral genome assembly and characterization hindrances from virus-host chimeric reads; a refining approach. PLoS Computational Biology, 17(8), e1009304. (Corresponding author).
  36. Spanakis, N.*, Kassela, K.*, Dovrolis, N.*, Bampali, M., Gatzidou, E., Kafasi, A., ... & Karakasiliotis, I. (2021). A main event and multiple introductions of SARS‐CoV‐2 initiated the COVID‐19 epidemic in Greece. Journal of medical virology, 93(5), 2899-2907. (Equal contribution).
  37. Andreou, N.-P.; Legaki, E.; Dovrolis, N.; Boyanov, N.; Georgiou, K.; Gkouskou, K.; Gazouli, M. B- cell activating factor (BAFF) expression is associated with Crohn's disease and can serve as a potential prognostic indicator of disease response to Infliximab treatment. Digestive and Liver Disease 2020, https://doi.org/10.1016/j.dld.2020.11.030
  38. Ramic J, Milosevic I, Mavija Z, Lojo-Kadric N, Hadzic M, Vidovic S, Niesler B, Dovrolis N, Gazouli M, Pojskic N, Pojskic L. Fecal Microbiome Diversity in Irritable Bowel Syndrome (IBS) Clinical Subtypes. Archives of Clinical and Biomedical Research. 2021;5:125-36.
  39. Mavragani, C.P.; Nezos, A.; Dovrolis, N.; Andreou, N.-P.; Legaki, E.; Sechi, L.A.; Bamias, G.; Gazouli, M. Type I and II Interferon Signatures Can Predict the Response to Anti-TNF Agents in Inflammatory Bowel Disease Patients: Involvement of the Microbiota. Inflamm. Bowel Dis. 2020, 10.1093/ibd/izaa216, doi:10.1093/ibd/izaa216.
  40. Dovrolis, N., Michalopoulos, G., Theodoropoulos, G.E., Arvanitidis, K., Kolios, G., Sechi, L.A., Eliopoulos, A.G. and Gazouli, M., 2020. The Interplay between Mucosal Microbiota Composition and Host Gene-Expression is Linked with Infliximab Response in Inflammatory Bowel Diseases. Microorganisms, 8(3), p.438.
  41. Gazouli, M.*, Dovrolis, N.*, Franke, A., Spyrou, G. M., Sechi, L. A., & Kolios, G. (2019). Differential genetic and functional background in inflammatory bowel disease phenotypes of a Greek population: a systems bioinformatics approach. Gut Pathogens, 11(1), 31. (Equal contribution).
  42. Dovrolis, N., Kolios, G., Spyrou, G. M., & Maroulakou, I. (2017). Computational profiling of the gut–brain axis: microflora dysbiosis insights to neurological disorders. Briefings in bioinformatics.
  43. Dovrolis, N., Filidou, E., & Kolios, G. (2019). Systems biology in inflammatory bowel diseases: on the way to precision medicine. Annals of gastroenterology, 32(3), 233.
  44. Dovrolis, N., Drygiannakis, Ι., Filidou, Ε., Kandilogiannakis, L., Arvanitidis, K., Tentes, I., Kolios, G., Valatas, V., (2018) Gut microbial signatures underline complicated Crohn’s Disease but vary between cohorts; an in silico approach, Inflammatory Bowel Diseases
  45. Dovrolis, N., Kolios, G., Spyrou, G., & Maroulakou, I. (2017). Laying in silico pipelines for drug repositioning: a paradigm in ensemble analysis for neurodegenerative diseases. Drug Discovery Today.
  46. Dietze, S., Taibi, D., Yu, H.Q., Dovrolis, N., 2015. A Linked Dataset of medical educational resources. Br J Educ Technol n/a–n/a. doi:10.1111/bjet.12276
  47. Dietze, S., Kaldoudi, E., Dovrolis, N., Giordano, D., Spampinato, C., Hendrix, M., Protopsaltis, A., Taibi, D., Yu, H. Q. (2013), Socio-semantic Integration of Educational Resources – the Case of the mEducator Project, in Journal of Universal Computer Science (J.UCS), Vol. 19, No. 11, pp. 1543-1569.
  48. Alexandridou, Anastasia, Nikolas Dovrolis, George Th Tsangaris, Konstantina Nikita, and George Spyrou. "PepServe: a web server for peptide analysis, clustering and visualization." Nucleic Acids Research 39, no. suppl 2 (2011): W381-W384.
  49. Kaldoudi, Eleni, Nikolas Dovrolis, S. Konstantinidis, and Panagiotis D. Bamidis. "Depicting educational content repurposing context and inheritance." Information Technology in Biomedicine, IEEE Transactions on 15, no. 1 (2011): 164-170.
  50. Kaldoudi, Eleni, Nicolas Dovrolis, Stathis Konstantinidis, and P. D. Bamidis. "Social networking for learning object repurposing in medical education." The Journal on Information Technology in Healthcare 7, no. 4 (2009): 233-243.
Book chapters
  1. Gazouli, Maria, Theodoropoulos, George. Gut Microbiome-Related Diseases and Therapies. ISBN 978-3-030-59642-2. Chapter 2. N. Dovrolis. In silico metagenomics analysis
  2. S. Stefanut, D. Gorgan, E. Kaldoudi, N. Dovrolis, S. Dietze, , “Creating Education Resources for Medical Education in the Web2.0/Web3.0 Era”, Chapter 15 in: T. Issa, P. Isaías and P. Kommers (eds.), “Information Systems and Technology for Organizations in a Networked Society”, pp. 275-294, IGI Global, Hershey, PA, USA, 2013 (in press) (ISBN 978-1-4666-4062-7) (invited, peer- reviewed)
  3. Giordano D., Dietze S., Spampinato C., Taibi D., Kaldoudi E., Dovrolis N., Mitsopoulou E., Yu H. Q., Konstantinidis S., Charalampos B., Bamidis P. (2011). Towards linking educational resources on the web through clustering and enrichment: the mEducator schema. In: Bamidis P, L. Despotova-Toleva, V. Anastasov, editors. E-education E-science. Plovdiv, Bulgaria: Medical Publishing VAP; 2011 (ISBN 978-960-243-682-0).
Peer-reviewed conference papers
  1. Kaldoudi, E., & Dovrolis, N. (2013). Comorbidities Modeling for Supporting Integrated Care in Chronic Cardiorenal Disease. In XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013: MEDICON 2013, 25-28 September 2013, Seville, Spain (pp. 1362-1365). Springer International Publishing.
  2. Eleni Kaldoudi, Nikolas Dovrolis. Semantic Social Networks for Integrated Healthcare. 14th Working Conference on Virtual Enterprises, (PROVE), Sep 2013, Dresden, Germany. pp.729-736, 10.1007/978-3-642-40543-3_76. hal-01463268
  3. Dovrolis, N., Stefanut, T., Dietze, S., Yu, H. Q., Valentine, C., & Kaldoudi, E. (2012). Semantic annotation and linking of medical educational resources. In 5th European Conference of the International Federation for Medical and Biological Engineering: 14–18 September 2011, Budapest, Hungary (pp. 1400-1403). Springer Berlin Heidelberg.
  4. Hendrix, M., Taibi, D., Dietze, S., Protopsaltis, A., Dunwell, I., Mitsopoulou, E., ... & Kaldoudi, E. (2012, April). Technical Evaluation of The mEducator 3.0 Linked Data-based Environment for Sharing Medical Educational Resources. In LiLe@ WWW.
  5. Dietze, S., Yu, H. Q., Giordano, D., Kaldoudi, E., Dovrolis, N., & Taibi, D. (2012, March). Linked Education: interlinking educational Resources and the Web of Data. In Proceedings of the 27th annual ACM symposium on applied computing (pp. 366-371).
  6. Kaldoudi, E., Dovrolis, N., & Dietze, S. (2011, October). Information organization on the internet based on heterogeneous social networks. In Proceedings of the 29th ACM international conference on Design of communication (pp. 107-114).
  7. Kaldoudi, E., Dovrolis, N., Giordano, D., & Dietze, S. (2011, May). Educational Resources as Social Objects in Semantic Social Networks. In Linked Learning@ ESWC.
  8. Dietze, S., Kaldoudi, E., Dovrolis, N., Yu, H. Q., & Taibi, D. (2011). MetaMorphosis+-A social network of educational Web resources based on semantic integration of services and data.
  9. Yu, H. Q., Dietze, S., Li, N., Pedrinaci, C., Taibi, D., Dovrolls, N., ... & Domingue, J. (2011). A linked data-driven & service-oriented architecture for sharing educational resources.
  10. Konstantinidis, S. T., Dovrolis, N., Kaldoudi, E., & Bamidis, P. D. (2010). Geotagged repurposed educational content through mEducator social network enhances biomedical engineering education. In XII Mediterranean Conference on Medical and Biological Engineering and Computing 2010: May 27–30, 2010 Chalkidiki, Greece (pp. 967-970). Springer Berlin Heidelberg.
  11. Dovrolis, N., Konstantinidis, S. T., Bamidis, P. D., & Kaldoudi, E. (2009, November). Depicting educational content re-purposing context and inheritance. In 2009 9th International Conference on Information Technology and Applications in Biomedicine (pp. 1-4). IEEE.

Scientific service

Reviewing, editorial and scientific organization

Reviewer

Reviewer for more than 30 international journals and conferences, including scientific areas in bioinformatics, molecular medicine, microbiome research, IBD and systems biology.

Guest editor

Guest Editor in Frontiers in Systems Biology and Biomedicines.

Scientific organization

Programme committee member for Linked Learning workshops from 2011 to 2016, LALD 2012 and ACM SIGDOC 2011. Invited speaker at the 20th International Conference on Pharmaceutical Medicine, Athens, 2022.

Contact

Contact and profiles

Department of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

ndovroli[@]med.duth.gr ORCID 0000-0003-3832-9939 Google Scholar Scopus